Nhan L Tran Selected Research

TWEAK Receptor

1/2021	Elevated fibroblast growth factor-inducible 14 expression transforms proneural-like gliomas into more aggressive and lethal brain cancer.
6/2018	Differential expression of the TWEAK receptor Fn14 in IDH1 wild-type and mutant gliomas.
11/2014	Development of human serine protease-based therapeutics targeting Fn14 and identification of Fn14 as a new target overexpressed in TNBC.
4/2013	The TWEAK receptor Fn14 is a therapeutic target in melanoma: immunotoxins targeting Fn14 receptor for malignant melanoma treatment.
11/2009	Tumor necrosis factor-like weak inducer of apoptosis stimulation of glioma cell survival is dependent on Akt2 function.
11/2007	Identification of Fn14/TWEAK receptor as a potential therapeutic target in esophageal adenocarcinoma.
4/2006	TWEAK and Fn14: new molecular targets for cancer therapy?
4/2003	The human Fn14 receptor gene is up-regulated in migrating glioma cells in vitro and overexpressed in advanced glial tumors.

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Nhan L Tran Research Topics

Disease

50	Neoplasms (Cancer) 09/2021 - 09/2002
30	Glioma (Gliomas) 01/2021 - 03/2003
27	Glioblastoma (Glioblastoma Multiforme) 01/2021 - 03/2003
6	Brain Neoplasms (Brain Tumor) 01/2021 - 02/2005
6	Neoplasm Metastasis (Metastasis) 10/2015 - 04/2006
6	Breast Neoplasms (Breast Cancer) 11/2014 - 05/2008
4	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 09/2021 - 02/2013
2	Necrosis 01/2021 - 04/2013
2	Lung Neoplasms (Lung Cancer) 06/2020 - 12/2013
2	Autoimmune Diseases (Autoimmune Disease) 01/2019 - 11/2013
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2017 - 12/2013
2	Inflammation (Inflammations) 01/2017 - 11/2013
2	Carcinogenesis 12/2013 - 04/2006
2	Disease Progression 10/2013 - 11/2007
2	Carcinoma (Carcinomatosis) 04/2006 - 09/2002
1	Leukemia 10/2020
1	Triple Negative Breast Neoplasms 01/2020
1	Pancreatic Neoplasms (Pancreatic Cancer) 01/2020
1	Colorectal Neoplasms (Colorectal Cancer) 10/2019
1	Gliosarcoma 01/2018
1	Crohn Disease (Crohn's Disease) 01/2017
1	Genomic Instability 01/2017
1	Arthritis (Polyarthritis) 04/2016
1	Vascular Dementia (Subcortical Arteriosclerotic Encephalopathy) 02/2016
1	Alzheimer Disease (Alzheimer's Disease) 02/2016
1	Medulloblastoma 01/2016

Drug/Important Bio-Agent (IBA)

17	Proteins (Proteins, Gene)FDA Link 09/2021 - 04/2003
15	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 01/2021 - 02/2005
12	Small Interfering RNA (siRNA)IBA 03/2016 - 11/2004
10	Temozolomide (Temodar)FDA LinkGeneric 01/2021 - 03/2016
10	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2018 - 02/2005
9	Messenger RNA (mRNA)IBA 06/2018 - 04/2003
8	TWEAK ReceptorIBA 01/2021 - 04/2003
8	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 01/2020 - 10/2006
6	Guanine Nucleotide Exchange Factors (Guanine Nucleotide Exchange Factor)IBA 10/2020 - 12/2008
6	Pharmaceutical PreparationsIBA 11/2018 - 07/2012
5	NF-kappa B (NF-kB)IBA 08/2010 - 04/2006
4	Biological ProductsIBA 01/2021 - 02/2005
4	RNA (Ribonucleic Acid)IBA 01/2020 - 01/2017
4	Phosphotransferases (Kinase)IBA 01/2017 - 03/2003
4	IntegrinsIBA 04/2006 - 09/2002
3	Biomarkers (Surrogate Marker)IBA 06/2020 - 12/2013
3	GTP Phosphohydrolases (GTPases)IBA 10/2013 - 07/2012
2	Proteoglycans (Proteoglycan)IBA 09/2021 - 10/2015
2	ErbB Receptors (EGF Receptor)IBA 01/2021 - 07/2012
2	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2021 - 01/2012
2	MicroRNAs (MicroRNA)IBA 01/2021 - 01/2012
2	Rho Guanine Nucleotide Exchange FactorsIBA 11/2020 - 10/2018
2	Cell Surface ReceptorsIBA 01/2020 - 04/2013
2	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 11/2018 - 05/2005
2	DNA (Deoxyribonucleic Acid)IBA 06/2018 - 04/2006
2	Epidermal Growth Factor (EGF)IBA 01/2018 - 09/2012
2	Transcription Factors (Transcription Factor)IBA 02/2017 - 01/2013
2	GlycosaminoglycansIBA 01/2017 - 10/2015
2	rho GTP-Binding Proteins (rho GTP-Binding Protein)IBA 10/2013 - 07/2012
2	Tyrosine (L-Tyrosine)FDA Link 09/2013 - 03/2003
2	Monomeric GTP-Binding ProteinsIBA 09/2012 - 12/2008
2	Focal Adhesion Protein-Tyrosine KinasesIBA 01/2012 - 03/2003
2	Serine (L-Serine)FDA Link 11/2009 - 09/2005
2	Peptides (Polypeptides)IBA 06/2009 - 09/2005
2	LigandsIBA 05/2008 - 01/2007
2	Cadherins (E-Cadherin)IBA 04/2006 - 09/2002
2	matrigelIBA 10/2005 - 11/2004
2	Focal Adhesion Kinase 2IBA 05/2005 - 03/2003
1	Chondroitin Sulfates (Chondroitin Sulfate)IBA 09/2021
1	Plasminogen Activators (Plasminogen Activator)IBA 01/2021
1	Plasminogen Activator Inhibitor 1IBA 01/2021
1	Bevacizumab (Avastin)FDA Link 11/2020
1	rhoC GTP-Binding ProteinIBA 10/2020
1	Complement System Proteins (Complement)IBA 06/2020
1	Albumin-Bound Paclitaxel FDA Link 01/2020
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2020
1	Paclitaxel (Taxol)FDA LinkGeneric 01/2020
1	SCH772984IBA 01/2020
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2020
1	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 11/2019
1	PX-866IBA 11/2019
1	Erlotinib Hydrochloride (CP 358,774)FDA Link 11/2018
1	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 06/2018
1	AGI-5198IBA 06/2018
1	Decitabine FDA Link 06/2018
1	EnzymesIBA 06/2018
1	epidermal growth factor receptor VIIIIBA 01/2018
1	Aurintricarboxylic AcidIBA 02/2017
1	Aquaporins (Water Channels)IBA 01/2017
1	Monoclonal AntibodiesIBA 01/2017
1	Immunoglobulin A (IgA)IBA 01/2017
1	16S Ribosomal RNAIBA 01/2017
1	AntibodiesIBA 04/2016
1	Alkylating AgentsIBA 03/2016
1	propentofyllineIBA 02/2016
1	methylxanthineIBA 02/2016
1	Protein Kinases (Protein Kinase)IBA 01/2016
1	hemiasterlinIBA 10/2015

Therapy/Procedure

29	Therapeutics 09/2021 - 11/2003
10	Drug Therapy (Chemotherapy) 01/2021 - 10/2006
10	Radiotherapy 01/2020 - 10/2006
2	Precision Medicine 01/2017 - 08/2015
1	Intravenous Administration 01/2021
1	Biological Therapy 01/2017